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Structured Review

Chrom Tech chrom state (gm12878)
Chrom State (Gm12878), supplied by Chrom Tech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/chrom%2E+state+(gm12878)/hi+c+experimental+data+of+gm12878+cell+line/pmc07322865__13059_2020_2059_MOESM2_ESM-219-99-98
Average 90 stars, based on 1 article reviews
chrom state (gm12878) - by Bioz Stars, 2026-09
90/100 stars

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Related Articles

Binding Assay:

Article Title: Allele-specific DNA methylation is increased in cancers and its dense mapping in normal plus neoplastic cells increases the yield of disease-associated regulatory SNPs
Article Snippet: The ASM index SNP disrupts an ELF1_2 motif, with lower binding affinity and higher methylation on the REF allele, as predicted by the TF binding site occupancy model. A B GWAS SNP ASM SNP Hodgkin lymphoma (rs3806624), chronic lymphocytic leukemia (rs9880772) Chrom. state (GM12878) EOMES Methyl. diff. (ALT-REF) in DLBCL 1 0 -1 BATF_disc2 REF (PWM 11.8) ALT (PWM 9.8) EOMES LINC01980 rs3806624 23 kb chr3 51 kb GAGTTGGAG AAGTTGGAG SLC4A47 rs3806624 Methyl. diff. (ALT-REF) in GBM 1 0 -1 rs3806624 MAZ_1 REF (PWM 8.2) ALT (PWM 10.2) GGGGCGAG GGGGCAAG rs3806624 GWAS SNP ASM SNP Breast carcinoma (rs2754412) Chrom. state (GM12878) Methyl. diff. (ALT-REF) in MM 1 0 -1 ELF1_2 REF (PWM 8.70) ALT (PWM 10.70) HSD17B7P2 SEPT7P9 rs2754412 rs61837215 24 kb rs61837215 chr10 13 kb CGGGCGGAAGCC CGGGCCGAAGCC ZNF37A LOC100129055 SEPT7P9 Fig. S23 rs2581199 Fig. S24.

Methylation:

Article Title: Allele-specific DNA methylation is increased in cancers and its dense mapping in normal plus neoplastic cells increases the yield of disease-associated regulatory SNPs
Article Snippet: The ASM index SNP disrupts an ELF1_2 motif, with lower binding affinity and higher methylation on the REF allele, as predicted by the TF binding site occupancy model. A B GWAS SNP ASM SNP Hodgkin lymphoma (rs3806624), chronic lymphocytic leukemia (rs9880772) Chrom. state (GM12878) EOMES Methyl. diff. (ALT-REF) in DLBCL 1 0 -1 BATF_disc2 REF (PWM 11.8) ALT (PWM 9.8) EOMES LINC01980 rs3806624 23 kb chr3 51 kb GAGTTGGAG AAGTTGGAG SLC4A47 rs3806624 Methyl. diff. (ALT-REF) in GBM 1 0 -1 rs3806624 MAZ_1 REF (PWM 8.2) ALT (PWM 10.2) GGGGCGAG GGGGCAAG rs3806624 GWAS SNP ASM SNP Breast carcinoma (rs2754412) Chrom. state (GM12878) Methyl. diff. (ALT-REF) in MM 1 0 -1 ELF1_2 REF (PWM 8.70) ALT (PWM 10.70) HSD17B7P2 SEPT7P9 rs2754412 rs61837215 24 kb rs61837215 chr10 13 kb CGGGCGGAAGCC CGGGCCGAAGCC ZNF37A LOC100129055 SEPT7P9 Fig. S23 rs2581199 Fig. S24.

GWAS:

Article Title: Allele-specific DNA methylation is increased in cancers and its dense mapping in normal plus neoplastic cells increases the yield of disease-associated regulatory SNPs
Article Snippet: The ASM index SNP disrupts an ELF1_2 motif, with lower binding affinity and higher methylation on the REF allele, as predicted by the TF binding site occupancy model. A B GWAS SNP ASM SNP Hodgkin lymphoma (rs3806624), chronic lymphocytic leukemia (rs9880772) Chrom. state (GM12878) EOMES Methyl. diff. (ALT-REF) in DLBCL 1 0 -1 BATF_disc2 REF (PWM 11.8) ALT (PWM 9.8) EOMES LINC01980 rs3806624 23 kb chr3 51 kb GAGTTGGAG AAGTTGGAG SLC4A47 rs3806624 Methyl. diff. (ALT-REF) in GBM 1 0 -1 rs3806624 MAZ_1 REF (PWM 8.2) ALT (PWM 10.2) GGGGCGAG GGGGCAAG rs3806624 GWAS SNP ASM SNP Breast carcinoma (rs2754412) Chrom. state (GM12878) Methyl. diff. (ALT-REF) in MM 1 0 -1 ELF1_2 REF (PWM 8.70) ALT (PWM 10.70) HSD17B7P2 SEPT7P9 rs2754412 rs61837215 24 kb rs61837215 chr10 13 kb CGGGCGGAAGCC CGGGCCGAAGCC ZNF37A LOC100129055 SEPT7P9 Fig. S23 rs2581199 Fig. S24.



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